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Growth Hormone Abuse and Detection in Athletes
By Jerald Cook, MD, FACOEM

In Blog by Jerald Cook

Recombinant human growth hormone (rhGH) is a popular hormone of abuse for performance enhancement with athletes. It is developed through recombinant technology, using E. coli bacteria and human DNA to generate the hormone, reducing the immunogenicity of the hormone. It is difficult to differentiate endogenous and exogenous hormone in toxicology testing because the hormone that is generated in vitro is …

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Cocaine: Acute Toxicity and Presumptive Testing
By Jerald Cook, MD, FACOEM

In Blog by Jerald Cook

Cocaine remains a popular drug of abuse, and per HHS (2008) of 6.5 million US Federal workplace drug tests, about 40,000 were positive for cocaine in 2007. Drug testing for cocaine is based on the metabolite benzoylecogonine which is detectable in the user’s urine for 24 hours, possibly even up to 72 hours. Non-metabolized cocaine may only be detectable for …